The 3rd Harmoni-CA Conference will take place from 5 to 7 April 2006 in Osnabrueck, Germany. Focus of the conference is set by the priorities within the WFD framework activities for 2006. The organisers of the conference invite operational water managers, water policy makers, researchers and technology providers to exchange their experiences on their current work related to river basin management and the implementation of the WFD. In addition to those external contributions, Harmoni-CA will present synthesises on specific issues linked to the WFD and modelling on the outcomes of European research projects.